Effects of Lipophilic Extract of Viscum album L. and Oleanolic Acid on Migratory Activity of NIH/3T3 Fibroblasts and on HaCat Keratinocytes

Figure 2

(a) Effect of VALE and OA on wound closure of NIH/3T3 fibroblasts expressed in % of cells migrated to the wounded area. As positive control DMEM with 5% FCS and as negative control untreated samples (1% FCS) were used. Density of confluent cells without created wound was set as 100% wound closure. (b), (c) Effect of VALE and OA on the proliferation of NIH/3T3 fibroblasts was expressed as proliferation of cells compared to the untreated control. Results are expressed as means ± SE of 7 independent wound healing or 3 proliferation experiments, respectively. Significance levels are given compared to the negative control (*𝑃<0.05, **𝑃<0.01, ***𝑃<0.001, LSD-test).

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