Rhodiola crenulata Extract Alleviates Hypoxic Pulmonary Edema in Rats
Figure 5
Lung histology. Histological examination was performed by photomicrography (original magnification ×400). Exposure to hypoxia led to a disruption of the alveolar-capillary barrier as indicated by the arrow and congested vascular wall. Treatment with RCE maintained the integrity of the alveolar-capillary barrier from hypoxic insults. (a) Control, (b) RCE, 100 mg/kg, (c) hypoxia (H), (d) H + acetazolamide, 100 mg/kg, (e) H + RCE, 50 mg/kg, and (f) H + RCE, 100 mg/kg. Pictures depicted here represent three independent experiments.