Table 2: Pharmacokinetic parameters of tanshinons in 12 healthy volunteers after single- and multiple-dose administration of the ethanol extract of danshen.

PK parameterTanshinone ICryptotanshinoneTanshinone IIADihydrotanshinone I

(ng/mL)
(ng/mL)
(ng/mL)

Data are mean value ± SD.
: peak plasma concentration after single-dose administration of the danshen extract; : plasma trough concentration at the end of a dosing interval after multiple-dose administration of the danshen extract; : peak plasma concentration at the end of a dosing interval after multiple-dose administration of the danshen extract.