Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 5

Research Article

Relationship between EGF, TGFA, and EGFR Gene Polymorphisms and Traditional Chinese Medicine ZHENG in Gastric Cancer

Table 5

Parallel comparison of genotype distribution of EGF, TGFA, and EGFR gene SNPs between the arbitrary two types of ZHENG.

Type of ZHENG   ( )

SSD10.731 (0.005)10a
5.486 (0.019)10b
10.174 (0.001)11a6.618 (0.010)11a4.495 (0.034)11a

YDSH11.517 (0.003)12a
8.588 (0.014)13a

DQY9.502 (0.002)7a
6.647 (0.010)11a
4.241 (0.039)7a
6.247 (0.044)12a
6.247 (0.044)13a

DQB14.410 (0.001)12a
8.136 (0.004)12b
11.105 (0.004)13a
8.136 (0.004)13b
8.197 (0.017)15a
7.639 (0.006)15b
5.371 (0.020)5a
5.022 (0.025)9b
4.118 (0.042)11a
4.128 (0.042)11b
8.225 (0.016)14a
7.777 (0.005)14b
4.828 (0.028)12a8.616 (0.013)1a
4.292 (0.038)1b
8.885 (0.012)4a
7.341 (0.007)4b
3.884 (0.049)14b
4.586 (0.032)3b
8.213 (0.016)12a
5.632 (0.018)12b
7.693 (0.021)13a
5.632 (0.018)13b
8.850 (0.012)5a
6.527 (0.038)12a
5.929 (0.015)12b
6.332 (0.042)13a
5.929 (0.015)13b
6.865 (0.032)15a
4.624 (0.032)15b

DLS7.319 (0.026)2a
5.470 (0.019)2b

DHT9.502 (0.002)7a8.068 (0.005)7a4.159 (0.041)6b
12.092 (0.002)7a
11.846 (0.001)7b
5.124 (0.024)8b

SPM9.027 (0.011)1a
5.120 (0.024)1b
4.430 (0.035)8b
7.523 (0.023)2a
4.459 (0.035)2b
6.007 (0.050)4a
4.593 (0.032)4b

rs11568835, 2rs3733625, 3rs4444903, and 4rs11569017 are located in the EGF gene; 5rs3771527, 6rs3732253, 7rs11466285, and 8rs2166975 are located in the TGFA gene; 9rs6965469, 10rs17337023, 11rs1140475, 12rs884225, 13rs884904, 14rs763317, and 15rs2072454 are located in the EGFR gene. Namely, 2rs3733625, 5rs3771527, 6rs3732253, 7rs11466285, and 12rs884225 are located in the 3′ UTR; 4rs11569017, 8rs2166975, 10rs17337023, 11rs1140475, and 15rs2072454 are located in the exon region; 14rs763317 is located in intron region; 1rs11568835, 9rs6965469, and 13rs884904 are located in the 5′ near region; 3rs4444903 is located in the 5′ UTR.
aComparison of the three genotypes; bcomparison of wild genotype and mutant genotype.

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