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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 731385, 9 pages
Research Article

Kai-Xin-San, a Chinese Herbal Decoction Containing Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria, Stimulates the Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes

1Division of Life Science, Center for Chinese Medicine and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong
2Jiangsu Key Laboratory for High Technology Research of TCM Formulae and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, China

Received 7 June 2013; Revised 16 August 2013; Accepted 21 August 2013

Academic Editor: Paul Siu-Po Ip

Copyright © 2013 Kevin Yue Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1: Chemical fingerprint chromatograms of KXS formulae. (A): Fingerprint chromatograms of KXS formulae were made by HPLC-DAD at wavelength of 330 nm. The identification of 3, 6’-disinapoyl sucrose (1), α-asarone (8) and β-asarone (7) were shown in the chromatogram. (B): Fingerprint chromatograms of KXS were made by HPLC-MS/MS method at negative scan mode. The identification of ginsenoside Rg1 (2), Re (3), Rb1 (4), Rd (6) and pachymic acid (9) were shown in the chromatogram. The internal marker control was astragaloside IV (5). The experimental details were fully described in [13]. Representative chromatograms are shown, n = 3.

  1. Supplementary Figure