Beneficial Effect of 7-O-Galloyl-D-sedoheptulose, a Polyphenol Isolated from Corni Fructus, against Diabetes-Induced Alterations in Kidney and Adipose Tissue of Type 2 Diabetic db/db Mice

Table 1

Glucose, leptin, insulin, and C-peptide in serum.

Group	Dose (mg/kg body weight/day)	Glucose (mg/dL)	Leptin (ng/dL)	Insulin (ng/mL)	C-peptide (pg/mL)
𝑚/𝑚	—	186±25^c	2.30±0.32^c	1.82±0.06^b	177±15^c
𝑑𝑏/𝑑𝑏
Veh	—	791±42	20.24±0.29	3.72±0.45	1,983 ± 277
GS	20	745±31	18.51±0.75	2.68±0.11^a	1,135  ±  139^a
GS	100	683±41	17.57±0.87^a	2.40±0.04^b	970±142^b

𝑚/𝑚, Misty; Veh, vehicle-treated 𝑑𝑏/𝑑𝑏 mice; GS20, GS20 mg/kg body weight-treated 𝑑𝑏/𝑑𝑏 mice; GS100, GS100 mg/kg body weight-treated 𝑑𝑏/𝑑𝑏 mice. The results are presented as the means ± S.E.M. ^a𝑃<0.05, ^b𝑃<0.01, ^c𝑃<0.001 versus vehicle-treated 𝑑𝑏/𝑑𝑏 mouse values.