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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 746968, 6 pages
Research Article

Static Magnetic Field Effects on Impaired Peripheral Vasomotion in Conscious Rats

1Department of Mechanical Engineering and Science, Graduate School of Engineering, Kyoto University, Kyoto 606-8502, Japan
2Research Section for Magnetics, Product Development Department, Development Division, PIP Company, Osaka 540-0011, Japan
3Research Center for Frontier Medical Engineering, Chiba University, Chiba 263-8522, Japan
4Department of Physical Therapy, School of Health Science and Social Welfare, Kibi International University, Okayama 716-8508, Japan
5Department of Medical Engineering, Nara Medical University, Nara 634-8522, Japan

Received 9 August 2013; Accepted 7 November 2013

Academic Editor: Ke Ren

Copyright © 2013 Shenzhi Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We investigated the SMF effects on hemodynamics in the caudal artery-ligated rat as an in vivo ischemia model using noninvasive near-infrared spectroscopy (NIRS) combined with power spectral analysis by fast Fourier transform. Male Wistar rats in the growth stage (10 weeks old) were randomly assigned into four groups: (i) intact and nonoperated cage control ( ); (ii) ligated alone ( ); (iii) ligated and implanted with a nonmagnetized rod (sham magnet; ); and (vi) ligated and implanted with a magnetized rod ( ). After caudal artery ligation, a magnetized or unmagnetized rod (maximum magnetic flux density of 160 mT) was implanted transcortically into the middle diaphysis of the fifth caudal vertebra. During the experimental period of 7 weeks, NIRS measurements were performed in 3- , 5- , and 7-week sessions and the vasomotion amplitude and frequency were analyzed by fast Fourier transform. Exposure for 3–7 weeks to the SMF significantly contracted the increased vasomotion amplitude in the ischemic area. These results suggest that SMF may have a regulatory effect on rhythmic vasomotion in the ischemic area by smoothing the vasomotion amplitude in the early stage of the wound healing process.