Immunosuppression of the Trimellitic Anhydride-Induced Th2 Response by Novel Nonanatural Products Mixture in Mice

Figure 2

Experimental protocol and ear thickness in TMA-induced CHS mouse model. (a) Experimental protocol. (b) BALB/c mice were divided into naïve, sham (TMA), NPM-9 (250 mg/kg BW), and prednisolone groups (30 mg/kg BW). Ear epidermal thickness was measured by histological analysis (H&E staining). Values are presented as mean ± SD (𝑛=4 in each group). Data were analyzed by ANOVA followed by Student’s 𝑡 test. *𝑃<0.05, **𝑃<0.01, significantly different from the saline value.

(a)

(b)