Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses

Table 3

Molecular docking of S. baicalensis flavonoids into influenza A viruses NA1, NA2, and NA9.

Flavonoids	LigScore2_Dreiding			DockScore
	NA1^a	NA2^b	NA9^c	NA1^a	NA2^b	NA9^c
Baicalein	4.42	3.76	4.68	61.041	49.358	36.683
Baicalin	6.52	4.13	5.24	77.712	48.391	38.279
Apigenin	4.51	3.66	4.41	57.727	44.794	35.018
Chrysin	4.92	3.64	4.37	54.621	40.560	34.109
Tamiflu	5.67	3.67	4.16	54.409	33.117	33.935

 ^aAvian influenza virus A/Vietnam/1203/04 (H5N1).
^bInfluenza virus A/Tanzania/205/2010 (H3N2).
^cAvian influenza virus A/tern/Australia/G70c/75 (N9).