Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses

Table 5

Inhibitory effects of flavonoids of S. baicalensis on NA enzymatic activity.

Flavonoids	NA inhibition IC50 values (μM)
	Seasonal 2007 H1N1	Pandemic 2009 H1N1	PR8 H1N1	Seasonal 2009 H1N1	Seasonal 2009 H3N2
Baicalein	0.423 ± 0.069	0.287 ± 0.074	0.181	0.526 ± 0.084	0.436
Baicalin	2.55 ± 0.083	2.57 ± 0.077	2.754	5.84 ± 0.074	3.98
Apigenin	61.72	112.23	81.3	118.48 ± 0.06	83
Chrysin	109.64	465.11 ± 0.09	131.92	175.43 ± 0.70	194.93