Galangin Abrogates Ovalbumin-Induced Airway Inflammation via Negative Regulation of NF-B
Figure 9
Treatment with galangin suppresses TNF--induced NF-B activation in normal human ASMC. ASMC were cultured with 10 ng/mL TNF- in the presence or absence of 10 M galangin for 0, 1, 10, and 30 minutes. The level of NF-B P65 in the nucleus was measured by western blot (a). Cells were cultured with 10 ng/mL TNF-, or TNF- and galangin (1 M and 10 M), or TNF- and 10 M TPCA-1. The level of NF-B P65 in the nucleus was measured by western blot (b). Data are expressed as means SEM of three experiments. compared with the control group; compared with TNF- alone.
