The Extract of Litsea japonica Reduced the Development of Diabetic Nephropathy via the Inhibition of Advanced Glycation End Products Accumulation in db/db Mice

Figure 1

Renal histopathology and function. (a) Periodic acid-Schiff staining of glomeruli. ×400 magnification; (b) proteinuria in each group. NOR: normal mice; DM: diabetic db/db mice; LJE-100: DM treated with LJE (100 mg/kg); LJE-250: DM treated with LJE (250 mg/kg); MET: DM treated with metformin (350 mg/kg). All data are expressed as the mean ± SEM (𝑛=8). ^∗𝑃<0.01 versus the NOR group; ^#𝑃<0.01 versus the DM group.

(a)

(b)