Doinseunggitang Ameliorates Endothelial Dysfunction in Diabetic Atherosclerosis

Table 2

Effect of DYSGT on body weight, blood pressure, and plasma biomarker levels in ApoE KO mice.

	Parameter
	Body weight (g)		Systolic blood pressure (mmHg)		BUN	LDL cholesterol	TG
	Start	Final	Start	Final	(mg/dL)	(𝜇g/𝜇L)	(mg/dL)
Cont.	23.09 ± 0.90	28.58 ± 0.98	103.92 ± 2.00	105.42 ± 1.80	0.67 ± 0.05	0.19 ± 0.02	44.92 ± 4.81
ApoE KO	22.76 ± 0.83	37.18 ± 0.88**	103.08 ± 2.69	118.92 ± 2.26**	1.32 ± 0.05*	1.02 ± 0.06**	102.42 ± 6.67**
Ros.	21.96 ± 0.44	35.3 ± 0.87	100.92 ± 2.04	105.58 ± 1.69^##	0.60 ± 0.03^#	0.84 ± 0.04^#	51.75 ± 5.38^##
DYSGT	21.92 ± 0.66	35.17 ± 1.32	100.33 ± 3.35	106.25 ± 2.52^##	0.70 ± 0.04^#	0.86 ± 0.03^#	47.83 ± 5.55^##

Data are mean ± SE values (𝑛=12); *𝑃<0.05, **𝑃<0.01 versus control; ^#𝑃<0.05, ^##𝑃<0.01 versus ApoE KO. Cont.: control; ApoE KO: apolipoprotein E knockout; Ros: rosiglitazone; DYSGT: Doinseunggitang.