Achyrocline satureioides (Lam.) D.C. Hydroalcoholic Extract Inhibits Neutrophil Functions Related to Innate Host Defense
β2-integrin and L-selectin expression on neutrophils from animals treated with A. satureoides hydroalcoholic extract. Animals received orally (1) control (untreated animals), (2) vehicle (PBS/ethanol 10%), or (3) A. satureoides (100 mg/kg). Neutrophils were incubated with PBS or LPS from E. coli 026:B6 (5 μg/mL) for 60 min at 37°C. (a) The percentage of β2-integrin-positive neutrophils and (b) the percentage of L-selectin-positive neutrophils. Data are expressed as mean ± S.E.M. of 5-6 animals in each group. Statistical analysis was performed using ANOVA followed by Tukey’s test. versus respective LPS-stimulated control.
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