Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 5

Research Article

Achyrocline satureioides (Lam.) D.C. Hydroalcoholic Extract Inhibits Neutrophil Functions Related to Innate Host Defense

Figure 5

Effects of A. satureoides hydroalcoholic extract on in vivo leukocyte migration induced by LPS, LTB-4, and CINC-1 secretion. Air pouch animals received orally (1) sham (air pouch induced without treatment), (2) vehicle (PBS/ethanol 10%), (3) indomethacin (30 mg/kg), or (4) A. satureoides (100 mg/kg). After 1 h, LPSs from E. coli 026:B6 (1 mg/2 mL) or PBS were injected directly into the air pouch, and 1 h later, the number of cells in the pouch was quantified. (a) Number of neutrophils in the air pouch, (b) levels of LTB-4 on air pouch exudate, and (c) levels of CINC-1 secretion on air pouch exudate. Data are expressed as mean ± S.E.M. of 5-6 animals in each group. Statistical analysis was performed using ANOVA followed by Tukey’s test. and versus sham; , , and versus vehicle.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.