A New Type of Biphasic Calcium Phosphate Cement as a Gentamicin Carrier for Osteomyelitis
Figure 8
Antibacterial experiments of gentamicin-loaded α-TCP/HAP biphasic cement. The left test tube was control group that did not contain released gentamicin sulfate, and the right test tube contained various period of time of released gentamicin sulfate. At the end of release experiments (30 days) conducted with 4 wt%, 8 wt% and 16 wt% gentamicin sulfate, the concentration in the release medium are , and μg/mL, respectively. The gentamicin loaded α-TCP/HAP biphasic cement can release effective concentration of gentamicin sulfate to inhibit the growth both of staphylococcus aureus and pseudomonas aeruginosa for 30 days.
