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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 801457, 11 pages
Review Article

Roles of Chlorogenic Acid on Regulating Glucose and Lipids Metabolism: A Review

1Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong, Shang hai 201203, China
2Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 201203, China
3E-Institute of Traditional Chinese Internal Medicine of Shanghai Municipal Education Commission, 1200 Cailun Road, Pudong, Shanghai 201203, China

Received 24 May 2013; Revised 9 July 2013; Accepted 12 July 2013

Academic Editor: Yong-Qing Yang

Copyright © 2013 Shengxi Meng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Intracellular glucose and lipid metabolic homeostasis is vital for maintaining basic life activities of a cell or an organism. Glucose and lipid metabolic disorders are closely related with the occurrence and progression of diabetes, obesity, hepatic steatosis, cardiovascular disease, and cancer. Chlorogenic acid (CGA), one of the most abundant polyphenol compounds in the human diet, is a group of phenolic secondary metabolites produced by certain plant species and is an important component of coffee. Accumulating evidence has demonstrated that CGA exerts many biological properties, including antibacterial, antioxidant, and anticarcinogenic activities. Recently, the roles and applications of CGA, particularly in relation to glucose and lipid metabolism, have been highlighted. This review addresses current studies investigating the roles of CGA in glucose and lipid metabolism.