Research Article

Xuebijing Protects Rats from Sepsis Challenged with Acinetobacter baumannii by Promoting Annexin A1 Expression and Inhibiting Proinflammatory Cytokines Secretion

Figure 6

Enzyme-linked immunosorbent assay (ELISA) for serum levels of (a) IL-8 and (b) TNF-α. Expression levels of IL-8 and TNF-α in the normal-control, sepsis-control, and sepsis + XBJ groups at 6, 12, and 24 hours after injection were shown. Results indicated elevations of IL-8 and TNF-α in plasmas of rats of sepsis-control groups compared with those of normal-control groups at each monitored time point. The elevations of the two proinflammatory cytokines were both reduced after the administration of XBJ and they were most prominent in the sepsis + XBJ group at 24 hours after injection. , compared with the sepsis-control group at the same time point; , compared with the sepsis-control group at 6 hours after injection; and , compared with the sepsis + XBJ group at 6 hours after injection.
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