Apoptosis Induced by Tanshinone IIA and Cryptotanshinone Is Mediated by Distinct JAK/STAT3/5 and SHP1/2 Signaling in Chronic Myeloid Leukemia K562 Cells
Figure 1
Tanshinone IIA and cryptotanshinone exert cytotoxicity in K562 cells. (a) Chemical structures of tanshinone IIA (left) and cryptotanshinone (right). (b) Cells were treated with various concentrations of tanshinone IIA or cryptotanshinone (0, 10, 20, 40, or 80 μM) for 24 h. MTT assay was performed to evaluate the cytotoxicity.
