Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio

<table>Relative luminescence expression of (a) caspase 3/7, (b) caspase 8, and (c) caspase 9 in the HepG2 cells treated with 11.43 <i>μ</i>g/mL of ZER-HP<i>β</i>CD inclusion complex for 24, 48, and 72 h. Caspases 3/7, 8, and 9 were significantly increased compared to the control untreated cells.  <svg height="13.95" id="M46" style="vertical-align:-0.16379pt" version="1.1" viewbox="0 0 68.949997 13.95" width="68.949997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) compared with control.</table>

Evidence-Based Complementary and Alternative Medicine

fig10

Figure 10

Figure 10: Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 

Figure 10 | Inclusion Complex of Zerumbone with Hydroxypropyl-β-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 