Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio

<table>DNA analysis of ZER-HP<i>β</i>CD inclusion-complex-treated HepG2. Rapidly proliferating HepG2 cells exposed to 11.43 <i>μ</i>g/mL at (b) 24 h, (c) 48 h, (d) 72 h and (a) control were tested for DNA content. Panels are representative of DNA histograms obtained and subsequently analyzed for DNA content; whereby R1, R2, R3, and R5 indicate sub-G0/G1 (apoptosis cells), G0/G1, S, and G2/M phase, respectively. </table>

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Figure 5

Figure 5: Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 

Figure 5 | Inclusion Complex of Zerumbone with Hydroxypropyl-β-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 