Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio

<table>Human apoptosis proteome profiler array analysis in HepG2 cells treated with 11.43 <i>μ</i>g/mL of ZER-HP<i>β</i>CD inclusion complex for 48 h. Graph shows the difference between treated and control untreated cells. <svg height="13.95" id="M43" style="vertical-align:-0.16379pt" version="1.1" viewbox="0 0 68.949997 13.95" width="68.949997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> a significant difference (<svg height="11.375" id="M44" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) compared with control. </table>

Evidence-Based Complementary and Alternative Medicine

fig9

Figure 9

Figure 9: Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 

Figure 9 | Inclusion Complex of Zerumbone with Hydroxypropyl-β-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 