Bonellia albiflora: A Mayan Medicinal Plant That Induces Apoptosis in Cancer Cells

Figure 2

Effect of hexane root extract Bonellia macrocarpa on DNA fragmentation in KB cells. After the treatment of the cells with a concentration of 50 μg/mL of B. macrocarpa for 12 h, DNA was isolated and separated on 1.5% agarose gel. DNA was stained with ethidium bromide and visualized under UV light. Lanes 1 to 4: lane 1 (negative control): DNA collected from untreated KB cells after 18 h; lane 2 (positive control): DNA collected from KB cells treated with 50 μg/mL of etoposide after 18 h; lane 3: DNA collected from KB cells treated with 50 μg/mL of extract after 18 h; lane 4: DNA molecular weight marker.