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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 823453, 8 pages
http://dx.doi.org/10.1155/2013/823453
Research Article

Bonellia albiflora: A Mayan Medicinal Plant That Induces Apoptosis in Cancer Cells

Unidad de Investigación Médica Yucatán, Unidad Médica de Alta Especialidad, Centro Médico Ignacio García Téllez, Instituto Mexicano del Seguro Social, 41 No. 439 x 32 y 34, Colonia Industrial CP, 97150 Mérida, YUC, Mexico

Received 3 April 2013; Revised 31 May 2013; Accepted 1 June 2013

Academic Editor: Ulysses Paulino de Albuquerque

Copyright © 2013 Rosa Moo-Puc et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. M. Spieler, “World Health Organization, the special programme of research, development and research training in human reproduction task force on indigenous plants for fertility regulation,” Korean Journal of Pharmacognosy, vol. 12, pp. 94–97, 1981. View at Google Scholar
  2. R. M. Mendieta, Plantas Medicinales Del Estado De Yucatán, CECSA, Yucatán, México, 1st edition, 1981.
  3. G. Balam, Cosmogonia Y Uso Actual De Las Plantas Medicinales De Yucatán, Universidad Autónoma de Yucatán, Yucatán, México, 1992.
  4. G. M. Cragg and D. J. Newman, “Plants as a source of anti-cancer agents,” Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 72–79, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Osadao, El Libro del Judío o Medicina Doméstica, Descripción de las Virtudes de las Yerbas Medicinales de Yucatán, Mérida, Yucatan Mexico, 1834.
  6. E. Caamal-Fuentes, L. W. Torres-Tapia, P. Simá-Polanco, S. R. Peraza-Sánchez, and R. Moo-Puc, “Screening of plants used in Mayan traditional medicine to treat cancer-like symptoms,” Journal of Ethnopharmacology, vol. 135, no. 3, pp. 719–724, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Sánchez-Medina, L. M. Peña-Rodríguez, F. May-Pat et al., “Identification of sakurasosaponin as a cytotoxic principle from Jacquinia flammea,” Natural Product Communications, vol. 5, no. 3, pp. 365–368, 2010. View at Google Scholar · View at Scopus
  8. E. Caamal-Fuentes, L. W. Torres-Tapia, R. Cedillo-Rivera, R. Moo-Puc, and S. R. Peraza-Sánchez, “Bonediol, a new alkyl catechol from Bonellia macrocarpa,” Phytochemistry Letters, vol. 4, no. 3, pp. 345–347, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. B. Ståhl and M. Källersjö, “Reinstatement of Bonellia (Theophrastaceae),” Novon, vol. 14, no. 1, pp. 115–118, 2004. View at Google Scholar · View at Scopus
  10. R. Arellano, G. Flores, and G. Tun, “Leguminosae,” in Nomenclatura, Forma de Vida, Uso, Manejo y Distribución de las Especies Vegetales de la Península de Yucatán, pp. 312–380, Universidad Autónoma de Yucatán, Yucatán, México, 2003. View at Google Scholar
  11. F. Denizot and R. Lang, “Rapid colorimetric assay for cell growth and survival - Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability,” Journal of Immunological Methods, vol. 89, no. 2, pp. 271–277, 1986. View at Google Scholar · View at Scopus
  12. X. Tong, S. Lin, M. Fujii, and D.-X. Hou, “Echinocystic acid induces apoptosis in HL-60 cells through mitochondria-mediated death pathway,” Cancer Letters, vol. 212, no. 1, pp. 21–32, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. R. I. Geran, N. H. Greenberg, M. M. Macdonald, A. M. Schumacher, and B. J. Abbott, “Protocols for screening chemical agents and natural products against animal tumors and other biological systems,” Cancer Chemotherapy Reports, vol. 3, pp. 59–61, 1972. View at Google Scholar
  14. R. Moo-Puc, D. Robledo, and Y. Freile-Pelegrín, “In vitro cytotoxic and antiproliferative activities of marine macroalgae from Yucatán, Mexico,” Ciencias Marinas, vol. 35, no. 4, pp. 345–358, 2009. View at Google Scholar · View at Scopus
  15. C. Vonthron-Sénécheau, B. Weniger, M. Ouattara et al., “In vitro antiplasmodial activity and cytotoxicity of ethnobotanically selected Ivorian plants,” Journal of Ethnopharmacology, vol. 87, no. 2-3, pp. 221–225, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. A. L. Okunade and D. F. Wiemer, “Jacquinonic acid, an ant-repellent triterpenoid from Jacquinia pungens,” Phytochemistry, vol. 24, no. 6, pp. 1203–1205, 1985. View at Google Scholar · View at Scopus
  17. K. Bhattacharyya, T. Kar, P. K. Dutta, G. Bocelli, and L. Righi, “Dimethyl oleana-13(18),15(16)-diene-3β,28-diacetate,” Acta Crystallographica Section C, vol. 55, no. 6, pp. 992–994, 1999. View at Google Scholar · View at Scopus
  18. K. Bhattacharyya, T. Kar, P. Kumar, B. Achari, and G. Bocelli, “Oleana-12(13), 15(16)-diene-3α, 28 diyl diacetate,” Acta Cristallographica, vol. 56, no. 2, pp. 60–61, 2000. View at Google Scholar
  19. H. J. Lee, H. Y. Kang, C. H. Kim et al., “Effect of new rotenoid glycoside from the fruits of Amorpha fruticosa LINNE on the growth of human immune cells,” Cytotechnology, vol. 52, no. 3, pp. 219–226, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. P. Bontempo, D. Rigano, A. Doto et al., “Genista sessilifolia DC extracts induce apoptosis across a range of cancer cell lines,” Cell Proliferation, vol. 46, no. 2, pp. 183–192, 2013. View at Google Scholar
  21. J.-W. Chon, J.-H. Sung, E.-J. Hwang, and Y.-K. Park, “Chlorella methanol extract reduces lipid accumulation in and increases the number of apoptotic 3T3-L1 cells,” Annals of the New York Academy of Sciences, vol. 1171, pp. 183–189, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. K.-J. Jo, M.-R. Cha, M.-R. Lee, M.-Y. Yoon, and H.-R. Park, “Methanolic extracts of Uncaria rhynchophylla induce cytotoxicity and apoptosis in HT-29 human colon carcinoma cells,” Plant Foods for Human Nutrition, vol. 63, no. 2, pp. 77–82, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Nadova, E. Miadokova, L. Alfoldiova et al., “Potential antioxidant activity, cytotoxic and apoptosis-inducing effects of Chelidonium majus L. extract on leukemia cells,” Neuroendocrinology Letters, vol. 29, no. 5, pp. 649–652, 2008. View at Google Scholar · View at Scopus
  24. T. N. Hasan, G. Shafi, N. A. Syed et al., “Methanolic extract of Nigella sativa seed inhibits SiHa human cervical cancer cell proliferation through apoptosis,” Natural Product Communications, vol. 8, no. 2, pp. 213–216, 2013. View at Google Scholar
  25. C. P. Preethy, R. Padmapriya, V. S. Periasamy et al., “Antiproliferative property of n-hexane and chloroform extracts of Anisomelesmalabarica (L). R. Br. in HPV16-positive human cervical cancer cells,” Journal of Pharmacology and Pharmacotherapeutics, vol. 3, no. 1, pp. 26–34, 2012. View at Google Scholar
  26. A. Chicca, B. Adinolfi, E. Martinotti et al., “Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines,” Journal of Ethnopharmacology, vol. 110, no. 1, pp. 148–153, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. C.-J. Zheng, L. Li, W.-H. Ma, T. Han, and L.-P. Qin, “Chemical constituents and bioactivities of the liposoluble fraction from different medicinal parts of Crocus sativus,” Pharmaceutical Biology, vol. 49, no. 7, pp. 756–763, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. Y. Ahmed, M. H. Sohrab, S. M. Al-Reza, F. S. Tareq, C. M. Hasan, and M. A. Sattar, “Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum,” Food and Chemical Toxicology, vol. 48, no. 2, pp. 549–552, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. R. Chowdhury, R. B. Rashid, M. H. Sohrab, and C. M. Hasan, “12α-hydroxystigmast-4-en-3-one: a new bioactive steroid from Toona ciliata (Meliaceae),” Pharmazie, vol. 58, no. 4, pp. 272–273, 2003. View at Google Scholar · View at Scopus
  30. K. H. Kim, S. U. Choi, C. S. Kim, and K. R. Lee, “Cytotoxic steroids from the trunk of Berberis koreana,” Bioscience, Biotechnology and Biochemistry, vol. 76, no. 4, pp. 825–827, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. A. B. Awad and C. S. Fink, “Phytosterols as anticancer dietary components: evidence and mechanism of action,” Journal of Nutrition, vol. 130, no. 9, pp. 2127–2130, 2000. View at Google Scholar · View at Scopus
  32. I. M. Villasenor and A. P. Domingo, “Anticarcinogenicity potential of spinasterol isolated from squash flowers,” Teratogenesis, Carcinogenesis, and Mutagenesis, vol. 20, pp. 99–105, 2000. View at Google Scholar
  33. J. L. Ríos, I. Andújar, M. C. Recio, and R. M. Giner, “Lanostanoids from fungi: a group of potential anticancer compounds,” Journal of Natural Products, vol. 75, no. 11, pp. 2016–2044, 2012. View at Google Scholar
  34. L. Zhou, Y. Zhang, L. A. Gapter, H. Ling, R. Agarwal, and K.-Y. Ng, “Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poriacocos,” Chemical and Pharmaceutical Bulletin, vol. 56, no. 10, pp. 1459–1462, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. J. F. R. Kerr, C. M. Winterford, and B. V. Harmon, “Apoptosis: its significance in cancer and cancer therapy,” Cancer, vol. 73, no. 8, pp. 2013–2026, 1994. View at Google Scholar · View at Scopus
  36. R. R. Somasagara, M. Hegde, K. K. Chiruvella, A. Musini, B. Choudhary, and S. C. Raghavan, “Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice,” PLoS ONE, vol. 7, no. 10, Article ID e47021, 2012. View at Google Scholar
  37. J.-Q. Yu, Y. Yin, J.-C. Lei et al., “Activation of apoptosis by ethyl acetate fraction of ethanol extract of Dianthus superbus in HepG2 cell line,” Cancer Epidemiology, vol. 36, no. 1, pp. e40–e45, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. A. C. Tan, I. Konczak, I. Ramzan, and D. M.-Y. Sze, “Native Australian fruit polyphenols inhibit cell viability and induce apoptosis in human cancer cell lines,” Nutrition and Cancer, vol. 63, no. 3, pp. 444–455, 2011. View at Publisher · View at Google Scholar · View at Scopus
  39. H. C. Pal, I. Sehar, S. Bhushan, B. D. Gupta, and A. K. Saxena, “Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce apoptosis in leukemia HL-60 cells by Inula racemosa,” Toxicology in Vitro, vol. 24, no. 6, pp. 1599–1609, 2010. View at Publisher · View at Google Scholar · View at Scopus
  40. Y.-C. Tien, J.-Y. Lin, C.-H. Lai et al., “Carthamus tinctorius L. prevents LPS-induced TNFα signaling activation and cell apoptosis through JNK1/2-NFκB pathway inhibition in H9c2 cardiomyoblast cells,” Journal of Ethnopharmacology, vol. 130, no. 3, pp. 505–513, 2010. View at Publisher · View at Google Scholar · View at Scopus
  41. M. E. Juan, U. Wenzel, V. Ruiz-Gutierrez, H. Daniel, and J. M. Planas, “Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells,” Journal of Nutrition, vol. 136, no. 10, pp. 2553–2557, 2006. View at Google Scholar · View at Scopus
  42. M.-J. Liu, Z. Wang, H.-X. Li, R.-C. Wu, Y.-Z. Liu, and Q.-Y. Wu, “Mitochondrial dysfunction as an early event in the process of apoptosis induced by woodfordin I in human leukemia K562 cells,” Toxicology and Applied Pharmacology, vol. 194, no. 2, pp. 141–155, 2004. View at Publisher · View at Google Scholar · View at Scopus
  43. H. S. Choi, H. S. Seo, J. H. Kim, J. Y. Um, Y. C. Shin, and S. G. Ko, “Ethanol extract of Paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways,” Journal of Biomedical Science, vol. 19, article 82, 2012. View at Publisher · View at Google Scholar
  44. S. Pandey, S. J. Chatterjee, P. Ovadje, M. Mousa, and C. Hamm, “The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 129045, 11 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  45. P. Ovadje, C. Hamm, and S. Pandey, “Efficient induction of extrinsic cell death by dandelion root extract in human chronic Myelomonocytic Leukemia (CMML) cells,” PLoS ONE, vol. 7, no. 2, Article ID e30604, 2012. View at Publisher · View at Google Scholar · View at Scopus
  46. W.-S. Suh, Y. S. Kim, A. D. Schimmer et al., “Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL,” Leukemia, vol. 17, no. 11, pp. 2122–2129, 2003. View at Publisher · View at Google Scholar · View at Scopus
  47. K. H. Kim, H. S. Seo, H. S. Choi, I. H. Choi, Y. C. Shin, and S.-G. Ko, “Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells,” Archives of Pharmacal Research, vol. 34, no. 8, pp. 1363–1372, 2011. View at Publisher · View at Google Scholar · View at Scopus
  48. Z. D. Nassar, A. F. A. Aisha, N. Idris et al., “Koetjapic acid, a natural triterpenoid, induces apoptosis in colon cancer cells,” Oncology Reports, vol. 27, no. 3, pp. 727–733, 2012. View at Publisher · View at Google Scholar · View at Scopus
  49. H. Ling, L. Zhou, X. Jia, L. A. Gapter, R. Agarwal, and K.-Y. Ng, “Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells,” Molecular Carcinogenesis, vol. 48, no. 6, pp. 498–507, 2009. View at Publisher · View at Google Scholar · View at Scopus
  50. A. B. Awad, M. Chinnam, C. S. Fink, and P. G. Bradford, “β-Sitosterol activates Fas signaling in human breast cancer cells,” Phytomedicine, vol. 14, no. 11, pp. 747–754, 2007. View at Publisher · View at Google Scholar · View at Scopus