Research Article
Bonellia albiflora: A Mayan Medicinal Plant That Induces Apoptosis in Cancer Cells
Table 2
Cytotoxicity of organic fractions from methanolic extract of B. albiflora root bark and bonediol.
| | Extract | Cell lines CC50 μg/mL (selective index) | | MDCK | KB | HeLa | Hep-2 | SiHa |
| | Hexane | 148.48 | 2.73 (54.38) | 14.29 (10.39) | 15.48 (9.59) | 27.02 (5.49) | | Dichloromethane | NA | NA | NA | NA | NA | | Ethyl acetate | NA | NA | NA | NA | NA | | Aqueous | NA | NA | NA | NA | NA | | Bonediol | 139.71 | 80.60 (1.73) | 115.45 (1.21) | 92.50 (1.51) | 54.40 (2.56) | | Docetaxel | 1.10 | 0.23 (4.78) | 0.20 (5.50) | 0.08 (13.75) | 0.32 (3.43) |
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NA: no activity > 200 μg/mL.
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