Combination Therapy of Sophoraflavanone B against MRSA: In Vitro Synergy Testing

Table 3

Results of the combination of SPF-B + AMP against MRSA.

S. aureus	Agent	MIC (μg/mL)		FIC	FICI	Outcome
		Alone	SPF-B + AMP
ATCC 33591	SPF-B	15.6	3.9	0.25	0.75	Partial synergy
	AMP	500	250	0.5
DPS-1	SPF-B	15.6	3.9	0.25	0.75	Partial synergy
	AMP	250	125	0.5
DPS-2	SPF-B	31.25	3.9	0.12	0.62	Partial synergy
	AMP	125	62.5	0.5
DPS-3	SPF-B	31.25	15.6	0.5	0.62	Partial synergy
	AMP	250	31.25	0.12
DPS-4	SPF-B	31.25	15.6	0.5	0.53	Partial synergy
	AMP	62.5	1.95	0.03
DPS-5	SPF-B	31.25	7.8	0.25	0.75	Partial synergy
	AMP	62.5	31.25	0.5