Combination Therapy of Sophoraflavanone B against MRSA: In Vitro Synergy Testing

Table 4

Results of the combination of SPF-B + OXI against MRSA.

S. aureus	Agent	MIC (μg/mL)		FIC	FICI	Outcome
		Alone	SPF-B + OXI
ATCC 33591	SPF-B	15.6	3.9	0.25	0.75	Partial synergy
	OXI	500	250	0.5
DPS-1	SPF-B	15.6	3.9	0.25	0.31	Synergy
	OXI	500	31.25	0.06
DPS-2	SPF-B	31.25	7.8	0.25	0.75	Partial synergy
	OXI	500	250	0.5
DPS-3	SPF-B	31.25	15.6	0.5	0.62	Partial synergy
	OXI	500	62.5	0.12
DPS-4	SPF-B	31.25	7.8	0.25	0.31	Synergy
	OXI	1,000	62.5	0.06
DPS-5	SPF-B	31.25	7.8	0.25	0.75	Partial synergy
	OXI	500	250	0.5