Combination Therapy of Sophoraflavanone B against MRSA: In Vitro Synergy Testing

Table 7

Results of the combination of SPF-B + NOR against MRSA.

S. aureus	Agent	MIC (μg/mL)		FIC	FICI	Outcome
		Alone	SPF-B + NOR
ATCC 33591	SPF-B	15.6	3.9	0.25	0. 5	Synergy
	NOR	1,000	250	0.25
DPS-1	SPF-B	15.6	3.9	0.25	0.75	Partial synergy
	NOR	500	125	0.5
DPS-2	SPF-B	31.25	3.9	0.25	0.75	Partial synergy
	NOR	1,000	62.50	0.5
DPS-3	SPF-B	31.25	15.6	0.25	0.5	Synergy
	NOR	1,000	31.25	0.25
DPS-4	SPF-B	31.25	15.6	0.25	0.75	Partial synergy
	NOR	62.5	1.95	0.5
DPS-5	SPF-B	31.25	7.8	0.5	0.75	Partial synergy
	NOR	500	31.25	0.25