An n-of-1 Trial Service in Clinical Practice: Testing the Effectiveness of Liuwei Dihuang Decoction for Kidney-Yin Deficiency Syndrome

Table 5

Repeated measure of SF-36 total score.

Source	Sum of squares	df	Mean square	𝐹	𝑃
Group	10.150	1	10.150	0.000	0.985
Pair	60248.979	1.775	33936.371	10.660	0.000
Group * pair	3261.686	1.775	1837.206	0.577	0.543
Error (group)	2668184.506	92	29002.005
Error (pair)	519956.205	163.332	3183.425

Test statistics of Mauchly’s test of sphericity: 𝑊=0.873, 𝑃=0.002. Greenhouse-Geisser was used to adjust df. SF-36 total score improved significantly at different pair. No significant differences between LDD and placebo. No interaction between group and pair.