Oral Administration of Alkylglycerols Differentially Modulates High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
Figure 2
The effect of selachyl alcohol (SA) or batyl alcohol (BA) on TLR-4 signaling activated by LPS in mice primary adipocytes. Newly differentiated cells were pretreated with DMSO vehicle (−) or 10 μM SA or 10 μM BA for 24 h and then treated with 10 μg/L LPS for 6 h. (a) Phosphorylation of JNK (P-JNK-to-JNK ratio). (b) Phosphorylation of ERK (P-ERK-to-ERK ratio). (c) Expression of IκBα (IκBα-to-actin ratio). Levels of protein were measured by western blotting. Data are a mean of SE and corrected for loading. Significant differences between each group are indicated by different letters.
