Research Article

Gastrointestinal and Hepatotoxicity Assessment of an Anticancer Extract from Muricid Molluscs

Table 2

Mean (±S.D.) morphometric values for small intestine toxicity indicators in control mice (0.000 mg/g, = 4) and mice administered 0.125 mg/g ( ), 0.5 mg/g ( ), and 1.0 mg/g ( ) muricid extract (ME). Significant differences between controls and extract doses are indicated by * (Tukey, ; Mann-Whitney, ).

Intestine regionME dose
(mg/g)
Villous
height (cells/villi)
Villous cell density
(cells/µm)
Crypt depth
(µm)

Duodenum0.000
0.125
0.500
1.000

Ileum0.000
0.125
0.500
1.000