Hinokitiol, a Natural Tropolone Derivative, Offers Neuroprotection from Thromboembolic Stroke In Vivo

Figure 6

Effects of hinokitiol on the protein expressions of TNF-α in MCAO-reperfusion injury in rat cerebral homogenates. Rats were pretreated with hinokitiol (0.2 mg/kg or 0.5 mg/kg) before ischemia and compared with vehicle or sham control. All groups are represented as ipsilateral hemisphere. Data are expressed as the means ± SEM (𝑛=5). ^∗∗∗𝑃<0.01 compared with sham control group; ^#𝑃<0.05 and ^###𝑃<0.001 compared with vehicle control group.