Research Article

Herbal Medicine Goshajinkigan Prevents Paclitaxel-Induced Mechanical Allodynia without Impairing Antitumor Activity of Paclitaxel

Figure 2

Effects of paclitaxel (PTX) and Goshajinkigan (GJG) on tumor weight in mice with breast cancer. Tumor masses were isolated from mice shown in Figure 1 on day 26 after the 4T1 cell inoculation. The photographs show typical examples of tumor mass isolated. PTX (10 and 20 mg/kg) and vehicle (VH1) were injected intraperitoneally. GJG (1 g/kg) and vehicle (VH2) were administered orally. Values represent the means ± SEM for three to six animals. (Holm-Sidak multiple comparisons).
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