Research Article

Lectin from Crataeva tapia Bark Improves Tissue Damages and Plasma Hyperglycemia in Alloxan-Induced Diabetic Mice

Figure 5

Histopathological changes in hepatic tissue. (a) Control group—centrilobular vein (V), preserved hepatocytes (white arrows), and sinusoidal capillaries (thin arrows); (b) diabetic nontreated—centrilobular vein with many red blood cells (V), intense mitotic activity in hepatocytes (arrowheads), and the presence of sinusoidal capillaries (thin arrows); (c) diabetic treated with CrataBL (10 mg/kg)—centrilobular vein (V) and considerable mitotic activity in hepatocytes (arrowheads); (d) diabetic treated with CrataBL (20 mg/kg)—centrilobular vein (V) and preserved hepatocytes (arrowheads). Haematoxylin-eosin: 400x.
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