Erectogenic and Aphrodisiac Effects of Butea frondosa Koenig ex Roxb. in Rats: Involvement of Enzyme Inhibition
Table 1
Effect of vehicle, MEBF, and sildenafil on sexual behavior of young and aged rats.
Sexual activities (units)
Young rat ()
Aged rat ()
Vehicle
MEBF
Sildenafil
Vehicle
MEBF
Sildenafil
0th day
14th day
28th day
0th day
14th day
28th day
0th day
14th day
28th day
0th day
14th day
28th day
0th day
14th day
28th day
0th day
14th day
28th day
ML (seconds)
36.17 ± 1.76
37.17 ± 1.47
37.00 ± 1.03
44.83 ± 4.13
36.83 ± 3.26
27.17 ± 2.74$
38.00 ± 2.47
16.83 ± 0.81#
11.00 ± 0.61#
114.33 ± 7.31
120.00 ± 4.51
122.00 ± 5.03
137.25 ± 6.97
106.75 ± 9.17
81.00 ± 6.18$
123.33 ± 8.69
64.00 ± 8.74$
37.67 ± 2.33#
IL (seconds)
50.33 ± 1.98
48.67 ± 1.75
47.83 ± 1.83
64.00 ± 3.79
50.83 ± 3.18
36.83 ± 2.63#
52.83 ± 3.01
21.67 ± 1.04#
14.67 ± 0.71#
143.33 ± 5.46
148.67 ± 4.26
144.33 ± 7.54
167.00 ± 5.08
131.25 ± 8.50
92.00 ± 6.82#
150.33 ± 8.04
76.00 ± 8.33#
45.00 ± 4.04#
EL (seconds)
327.50 ± 8.71
331.33 ± 7.87
326.17 ± 6.77
305.5 ± 13.89
387.33 ± 19.05*
501.17 ± 25.45$
322 ± 6.75
620.5 ± 11.46#
899.33 ± 9.26#
187.33 ± 8.51
194.67 ± 8.09
190.67 ± 10.33
172.00 ± 9.04
267.50 ± 7.47#
355.25 ± 8.80#
195.00 ± 9.54
410.67 ± 7.54#
383.00 ± 15.13#
MF (number)
11.50 ± 0.76
12.00 ± 0.97
12.67 ± 0.97
9.50 ± 0.76
11.83 ± 0.87
14.17 ± 1.11
9.83 ± 0.31
18.50 ± 0.76#
23.00 ± 0.82#
5.00 ± 0.58
5.00 ± 0.58
5.33 ± 0.33
4.00 ± 0.41
7.00 ± 0.50
10.67 ± 0.76$
4.33 ± 0.67
11.67 ± 1.20#
15.00 ± 1.00#
IF (number)
10.50 ± 0.76
10.17 ± 0.79
10.33 ± 0.95
11.17 ± 0.95
13.17 ± 0.75*
25.00 ± 2.15#
11.33 ± 1.25
36.67 ± 0.97#
42.83 ± 1.04#
4.33 ± 0.88
4.33 ± 0.33
4.00 ± 0.58
3.50 ± 0.65
5.75 ± 0.48
9.75 ± 0.85#
3.00 ± 0.58
18.00 ± 0.58#
25.00 ± 0.58#
PEI (seconds)
230.50 ± 8.97
239.83 ± 8.09
238.67 ± 9.06
275.00 ± 7.14
240.33 ± 9.63
210.67 ± 7.92*
248.83 ± 6.46
210.50 ± 7.48*
172.67 ± 6.51#
357.00 ± 11.02
350.33 ± 12.77
354.33 ± 5.84
366.33 ± 17.08
330.75 ± 14.70
300.75 ± 12.47$
351.33 ± 10.87
304.33 ± 5.61
267.00 ± 3.46#
ML: mount latency, IL: intromission latency, EL: ejaculation latency, MF: mount frequency, IF: intromission frequency, and PEI: postejaculatory interval. , , , methanol extract of Butea frondosa (MEBF)/sildenafil versus vehicle (1% Tween 20). : number of animals. All the groups had 6 animals, but 50 percent of aged animals lost sexual function; therefore, those rats were not included for statistical analysis.
