Research Article

Melatonin Suppresses the Expression of 45S Preribosomal RNA and Upstream Binding Factor and Enhances the Antitumor Activity of Puromycin in MDA-MB-231 Breast Cancer Cells

Figure 3

Effect of melatonin on the survival genes and apoptotic proteins in MDA-MB-231 cells. (a) Effect of melatonin on survival genes (b) Effect of melatonin on procaspase 3 and PARP. Cells were treated with melatonin (3 mM) for 24 h. Western blotting analysis was performed with antibodies of above survival, apoptotic genes, and -actin.
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(a)
879746.fig.003b
(b)