Bioactive Fraction of Geopropolis from Melipona scutellaris Decreases Neutrophils Migration in the Inflammatory Process: Involvement of Nitric Oxide Pathway

Figure 3

Effect of the ethanolic extract of geopropolis (EEGP) and aqueous fraction (AF) on the levels of CXCL1/KC (a) and CXCL2/MIP-2 (b) 3 h after the injection of 500 μg/cavity of carrageenan in the peritoneal cavity. Mice were pretreated with vehicle (saline and carrageenan), EEGP, or aqueous fraction (10 mg/kg, s.c.). The data are expressed as mean ± SEM, 𝑛=5. Symbols indicate statistical difference (𝑃<0.05, Tukey test). ^#Compared to the saline group.

(a)

(b)