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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 925342, 7 pages
Review Article

A Review on Bioactivities of Perilla: Progress in Research on the Functions of Perilla as Medicine and Food

Center for Environment, Health and Field Sciences, Chiba University, Kashiwanoha 6-2-1, Kashiwa, Chiba 277-0882, Japan

Received 12 April 2013; Accepted 24 September 2013

Academic Editor: Wagner Vilegas

Copyright © 2013 Miho Igarashi and Yoshifumi Miyazaki. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Perilla is a useful pharmaceutical and food product and is empirically consumed by humans. However, its properties have not been evaluated extensively. In this review, we summarize the progress made in research, focusing on the bioactivities of perilla. There are many in vitro and animal studies on the cytostatic activity and antiallergic effects, respectively, of perilla and its constituents. However, its influence on humans remains unclear. Hence, investigating and clarifying the physiological effects of perilla and its constituents on humans are imperative in the future to adhere to the ideals of evidence-based medicine.