Evaluation of the Genotoxic Potential against H_𝟐O_𝟐-Radical-Mediated DNA Damage and Acute Oral Toxicity of Standardized Extract of Polyalthia longifolia Leaf

Table 5

Cytogenetic analysis of A. cepa root tips exposed to different concentrations of P. longifolia leaf and Fenton reagents.

Treatments			Chromosome aberrations
Concentration (µg/mL)	No. of cells	Mitotic Index	Stickiness	Bridges	C-mitosis	Vagrant	% of Aberrant cells
P. longifolia leaf
100	1069	0.424 ± 0.060*	4	3	3	4	1.31
250	1224	0.303 ± 0.045*	5	4	3	8	1.63
500	1046	0.209 ± 0.064*	10	12	7	8	3.54
Fenton reagent (FR)	1105	0.170 ± 0.046*	24	14	20	7	5.88
FR + P. longifolia (100 µg/mL)	1225	0.386 ± 0.042*	7	4	3	5	1.55
FR + Quercetin (10 µg/mL)	1239	0.401 ± 0.043*	4	3	2	3	1.07
Control (distilled water)	1194	0.503 ± 0.025	0	2	0	2	0.33

* P < 0.05 versus control (distilled water).