Review Article

Effects and Mechanisms of Chinese Herbal Medicine in Ameliorating Myocardial Ischemia-Reperfusion Injury

Table 2

Efficacy and mechanism of single Chinese herbs in the treatment of MIR.

Mechanism of action in TCM terminologyHerbMechanismBiomarker/TargetsIn vivo/In vitroReferences

Replenishing and moving Qi Rhodiola Promote angiogenesisVEGFR (Flt-1, KDR, and Tie-2)In vivo[106]
Euryale ferox (Makhana) AntioxidantTRP32, ROS, and Trx-1Both[53]
Aurantii Fructus Recovery of contractile dysfunctionPerfusion pressure, aortic flow, and coronary flowIn vivo[107]