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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 931283, 7 pages
Research Article

Visceral Nociceptive Afferent Facilitates Reaction of Subnucleus Reticularis Dorsalis to Acupoint Stimulation in Rats

1Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China
2Wuhan Integrated TCM and Western Medicine Hospital, Wuhan 430020, China
3Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China

Received 22 February 2013; Revised 18 April 2013; Accepted 23 April 2013

Academic Editor: Lijun Bai

Copyright © 2013 Liang Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To explore the area and sensitization variance of acupoint when internal organs are under pathological condition. To observe quantity-effect variance of subnucleus reticularis dorsalis (SRD) to electroacupuncture under both physiological and pathological conditions. To explain medulla oblongata mechanism of acupoint sensitization. Method. Mustard oil was imported into colon and rectum of 20 male SD rats in order to observe its influence on acupoint sensitization. SRD neuron activity was recorded. Visceral nociceptive stimulus was generated by colorectal distension (CRD). Quantity-effect variance of neuron activity to electroacupuncture to “Zusanli-Shangjuxu” area both before and after CRD was observed. Paired t-test is used for cross-group comparison; is deemed as of statistical differences. Result. Visceral inflammation could facilitate SRD neuron activity to acupoint stimulation. Visceral nociceptive afference could enhance neuron activity to acupoint acupuncture. Wide dynamic range (WDR) neuron activity caused by electroacupuncture increased when visceral nociception increased. Conclusion. The size and function of the acupoints comply with the functionality of the internal organs. The sensitive degree of acupoints changed according to malfunction of internal organs.