Protective Effect of Free and Bound Polyphenol Extracts from Ginger (Zingiber officinale Roscoe) on the Hepatic Antioxidant and Some Carbohydrate Metabolizing Enzymes of Streptozotocin-Induced Diabetic Rats

Table 2

Effect of administration of polyphenols from Z. officinale on antioxidant enzymes’ activities in the liver of normal and streptozotocin-diabetic rats.

Group	U/mg protein
	CAT	SOD	GPx	GSH
Normal control	65.20 ± 2.89^a	33.60 ± 1.73^a	51.63 ± 2.75^a	16.21 ± 1.16^a
Diabetic control	11.25 ± 1.16^b	7.83 ± 1.21^b	19.63 ±1.24^b	28.74 ± 2.67^b
Diabetic + free	34.56 ± 2.31^c	24.35 ± 2.17^c	25.47 ± 1.68^b	23.37 ± 1.19^b
Diabetic + bound	21.27 ± 1.83^d	18.53 ± 1.17^d	23.75 ± 2.76^b	25.46 ± 1.70^b
Diabetic + GBN	40.42 ± 1.76^c	25.45 ± 1.29^c	35.20 ± 1.79^c	20.26 ± 1.12^c

Values are mean ± S.E.M. of 8 rats. Test values down the vertical columns carrying different superscripts for each parameter are significantly different (P < 0.05). CAT: catalase, SOD: superoxide dismutase, GPx: glutathione peroxidase, GSH: reduced glutathione.