Protective Effect of Free and Bound Polyphenol Extracts from Ginger (Zingiber officinale Roscoe) on the Hepatic Antioxidant and Some Carbohydrate Metabolizing Enzymes of Streptozotocin-Induced Diabetic Rats

Table 3

Effect of administration of polyphenols from Z. officinale on carbohydrate metabolic enzymes’ activities in the liver of normal and streptozotocin-diabetic rats.

Group	U/mg protein
	HK	PFK	F-1,6-BP	G-6-P
Normal control	2.95 ± 0.03^a	3.81 ± 0.06^a	3.56 ± 0.58^a	10.50 ± 1.16^a
Diabetic control	0.93 ± 0.36^a	2.56 ± 0.23^a	8.42 ±1.16^b	25.62 ± 2.89^b
Diabetic + free	2.55 ± 0.23^a	3.34 ± 0.17^a	4.23 ± 0.29^a	13.25 ± 1.16^a
Diabetic + bound	2.17 ± 0.29^a	2.86 ± 0.58^a	5.96 ± 0.58^c	15.63 ± 1.73^a
Diabetic + GBN	2.68 ± 0.21^a	3.69 ± 0.17^a	4.06 ± 0.51^a	12.36 ± 2.05^a

Values are mean ± S.E.M. of 8 rats. Test values down the vertical columns carrying different superscripts for each parameter are significantly different (P < 0.05). HK: hexokinase, PFK: phosphofructokinase, F-1,6-BP: fructose-1,6-biphosphatase, G-6-P: glucose-6-phosphatase.