Acetylshikonin, a Novel AChE Inhibitor, Inhibits Apoptosis via Upregulation of Heme Oxygenase-1 Expression in SH-SY5Y Cells

<table>Acetylshikonin modulated H<sub>2</sub>O<sub>2</sub>-induced apoptosis-related protein expression in both SH-SY5Y (a) and PC12 (b) cells. The cells were treated with desired concentration of acetylshikonin for 12 hours and then stimulated with H<sub>2</sub>O<sub>2</sub> (500 <i>μ</i>M) for 1 hour, and the apoptosis-related protein expression was detected by western blot.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: Acetylshikonin, a Novel AChE Inhibitor, Inhibits Apoptosis via Upregulation of Heme Oxygenase-1 Expression in SH-SY5Y Cells 