Epimedium Flavonoids Counteract the Side Effects of Glucocorticoids on Hypothalamic-Pituitary-Adrenal Axis

<table>Effects of EFs on plasma ACTH and corticosterone level of rats. (a) Plasma ACTH level was measured by ELISA in control, corticosterone, and combined use of corticosterone and EFs. (b) Plasma corticosterone level was measured by ELISA after treatment with saline (control), corticosterone, and combined use of corticosterone and EFs. <svg height="13.95" id="M22" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control group. <svg height="15.775" id="M24" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 67.387497 15.775" width="67.387497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus corticosterone-only group.</table>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Epimedium Flavonoids Counteract the Side Effects of Glucocorticoids on Hypothalamic-Pituitary-Adrenal Axis 