Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 938764, 17 pages
http://dx.doi.org/10.1155/2013/938764
Research Article

A Systems-Pharmacology Analysis of Herbal Medicines Used in Health Improvement Treatment: Predicting Potential New Drugs and Targets

1College of Life Science, Northwest University, Xi’an, Shaanxi 710000, China
2Department of Materials Science and Chemical Engineering, Dalian University of Technology, Dalian, Liaoning 116000, China
3Center of Bioinformatics, College of Life Science, Northwest A & F University, Yang ling, Shaanxi 712100, China
4School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong 999077, Hong Kong
5Lab of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116000, China

Received 29 April 2013; Revised 23 September 2013; Accepted 4 October 2013

Academic Editor: Y. Ohta

Copyright © 2013 Jianling Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [24 citations]

The following is the list of published articles that have cited the current article.

  • María Alejandra Alvarezpp. 1–161, 2014. View at Publisher · View at Google Scholar
  • Jinlong Ru, Peng Li, Jinan Wang, Wei Zhou, Bohui Li, Chao Huang, Pidong Li, Zihu Guo, Weiyang Tao, Yinfeng Yang, Xue Xu, Yan Li, Yonghua Wang, and Ling Yang, “TCMSP: a database of systems pharmacology for drug discovery from herbal medicines,” Journal of Cheminformatics, vol. 6, 2014. View at Publisher · View at Google Scholar
  • Abdelaziz Ghanemi, and Besma Boubertakh, “Shorter and Sturdier Bridges Between Traditional Chinese Medicines and Modern Pharmacology,” Saudi Pharmaceutical Journal, 2014. View at Publisher · View at Google Scholar
  • Xiao Ma, Ji Wang, Xuan He, Yanling Zhao, Jiabo Wang, Ping Zhang, Yun Zhu, Lin Zhong, Quanfu Zheng, and Xiaohe Xiao, “Large Dosage of Chishao in Formulae for Cholestatic Hepatitis: A Systematic Review and Meta-Analysis,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, pp. 1–10, 2014. View at Publisher · View at Google Scholar
  • Yingying Guo, Yan Ding, Feifei Xu, Baoyue Liu, Zinong Kou, Wei Xiao, and Jingbo Zhu, “Systems pharmacology-based drug discovery for marine resources: An example using sea cucumber (Holothurians),” Journal of Ethnopharmacology, vol. 165, pp. 61–72, 2015. View at Publisher · View at Google Scholar
  • Chang-xiao Liu, Rui Liu, Hui-rong Fan, Xue-feng Xiao, Xiao-peng Chen, Hai-yu Xu, and Yan-ping Lin, “Network Pharmacology Bridges Traditional Application and Modern Development of Traditional Chinese Medicine,” Chinese Herbal Medicines, vol. 7, no. 1, pp. 3–17, 2015. View at Publisher · View at Google Scholar
  • Yu-feng Liu, Ni Ai, Anthony Keys, Xiao-hui Fan, and Min-jun Chen, “Network Pharmacology for Traditional Chinese Medicine Research: Methodologies and Applications,” Chinese Herbal Medicines, vol. 7, no. 1, pp. 18–26, 2015. View at Publisher · View at Google Scholar
  • Feifei Xu, Yan. Ding, Yingying Guo, Baoyue Liu, Zinong Kou, Wei Xiao, and Jingbo Zhu, “Anti-osteoporosis effect of Epimedium via an estrogen-like mechanism based on a system-level approach,” Journal of Ethnopharmacology, 2015. View at Publisher · View at Google Scholar
  • Mohammed Abdullah Al Mansour, Abdullah Almudaiheem, Waqas Sami Mahmoud, Khalid Altohami Medani, Naseem Akhtar Qureshi, Abdullah Mn Al-Bedah, Mohammed Othman AlRukban, Ibrahim S Elsubai, Elsadiq Yousif Mohamed, Ahmed Tawfik El Olemy, Asim Ah Khalil, Mohamed Km Khalil, and Meshari Saleh Alqaed, “Medical students' knowledge, attitude, and practice of complementary and alternative medicine: a pre-and post-exposure survey in Majmaah University, Saudi Arabia.,” Advances in medical education and practice, vol. 6, pp. 407–20, 2015. View at Publisher · View at Google Scholar
  • Jing-Bo Zhu, Zi-Nong Kou, Dan Liu, Yong-Hua Wang, Yan Ding, and Wei Xiao, “Potential mechanism of Ginkgo Folium extract used in treatment of gout based on network pharmacology,” Chinese Traditional and Herbal Drugs, vol. 47, no. 15, pp. 2693–2700, 2016. View at Publisher · View at Google Scholar
  • Wei-Wei Su, and Pan-Lin Li, “Recent progress in applying network pharmacology to research of Chinese materia medica,” Chinese Traditional and Herbal Drugs, vol. 47, no. 16, pp. 2938–2942, 2016. View at Publisher · View at Google Scholar
  • Paramasivan Poornima, Jothi Dinesh Kumar, Qiaoli Zhao, Martina Blunder, and Thomas Efferth, “Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature,” Pharmacological Research, 2016. View at Publisher · View at Google Scholar
  • Hong Xin, Xiao-Yi Qi, Jing-Jing Wu, Xin-Xin Wang, Yan Li, James Y. Hong, Wei He, Wei Xu, Guang-Bo Ge, and Ling Yang, “Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases,” Food And Chemical Toxicology, vol. 90, pp. 112–122, 2016. View at Publisher · View at Google Scholar
  • Ya-Jing Liu, Dan-Dan Wang, Yong-Shan Jiang, Guang-Bo Ge, Xin-Miao Liang, Ling Yang, Shi-Yang Li, Jie Hou, and Yan-Fang Liu, “Identification and characterization of naturally occurring inhibitors against human carboxylesterase 2 in White Mulberry Root-bark,” Fitoterapia, vol. 115, pp. 57–63, 2016. View at Publisher · View at Google Scholar
  • Baixia Zhang, Yanwen Li, Yanling Zhang, Zhiyong Li, Tian Bi, Yusu He, Kuokui Song, and Yun Wang, “ITPI: Initial Transcription Process-Based Identification Method of Bioactive Components in Traditional Chinese Medicine Formula,” Evidence-Based Complementary and Alternative Medicine, vol. 2016, pp. 1–7, 2016. View at Publisher · View at Google Scholar
  • Yin Kwan Chung, Jihang Chen, and Kam Ming Ko, “Spleen Function and Anxiety in Chinese Medicine: A Western Medicine Perspective,” Chinese Medicine, vol. 07, no. 03, pp. 110–123, 2016. View at Publisher · View at Google Scholar
  • Mohammed Abdullah Al Mansour, Abdullah M. N. Al-Bedah, Ibrahim S. Elsubai, Mohammed Othman Al-Rukban, Elsadig Yousif Mohamed, Ahmed Tawfik El Olemy, Asim A. H. Khalil, Mohamed K. M. Khalil, Meshari Saleh Alqaed, Abdullah Almudaiheem, Waqas Sami Mahmoud, Khalid Altohami Medani, Gazzaffi Ibrahim Mahjoub Ali, and Naseem A. Qureshi, “Medical Students' Perceptions Of Complementary And Alternative Medicine Therapies: A Pre- And Post-Exposure Survey In Majmaah University, Saudi Arabia,” African Journal Of Traditional Complementary And Alternative Medicines, vol. 13, no. 1, pp. 6–16, 2016. View at Publisher · View at Google Scholar
  • Dan-Dan Wang, Li-Wei Zou, Qiang Jin, Jie Hou, Guang-Bo Ge, and Ling Yang, “Recent progress in the discovery of natural inhibitors against human carboxylesterases,” Fitoterapia, vol. 117, pp. 84–95, 2017. View at Publisher · View at Google Scholar
  • Mi Hye Kim, You Yeon Choi, Kwang Seok Ahn, Jae-Young Um, Seok-Geun Lee, and Woong Mo Yang, “Immunomodulatory effects of Pseudostellaria heterophylla (Miquel) Pax on regulation of Th1/Th2 levels in mice with atopic dermatitis,” Molecular Medicine Reports, vol. 15, no. 2, pp. 649–656, 2017. View at Publisher · View at Google Scholar
  • Mohamed E.M. Saeed, Awadh Alim, Thomas Efferth, Elhaj Mirghani, Zahir Yassin, Elfatih Saeed, Hassan E. Khalid, and Salah Daak, “Integration of phytochemicals and phytotherapy into cancer precision medicine,” Oncotarget, vol. 8, no. 30, pp. 50284–50304, 2017. View at Publisher · View at Google Scholar
  • Xu Wang, Zhonghong Wei, Yuzhu Cao, Qi Jia, Jinqiu Zhong, Peiliang Shen, Yin Shen, Siliang Wang, Yin Lu, Suyun Yu, Lichuan Chen, and Yanhong Pan, “NiaoDuQing granules relieve chronic kidney disease symptoms by decreasing renal fibrosis and anemia,” Oncotarget, vol. 8, no. 34, pp. 55920–55937, 2017. View at Publisher · View at Google Scholar
  • Shuo Gu, and Jianfeng Pei, “Chinese Herbal Medicine Meets Biological Networks of Complex Diseases: A Computational Perspective,” Evidence-Based Complementary and Alternative Medicine, vol. 2017, pp. 1–7, 2017. View at Publisher · View at Google Scholar
  • Qian Ru Zhang, Zhang Feng Zhong, Wei Sang, Wei Xiong, Hong Xun Tao, Guan Ding Zhao, Zhi Xin Li, Anfernee Kai Wing Tse, Yuan Jia Hu, Hua Yu, and Yi Tao Wang, “Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: combined computational predictions and experimental investigations,” Journal of Ethnopharmacology, 2018. View at Publisher · View at Google Scholar
  • Yong Deng, Han Bangxing, Hu Dejun, Zhao Jing, and Li Shaoping, “Qualitation and quantification of water soluble non-starch polysaccharides from Pseudostellaria heterophylla in China using saccharide mapping and multiple chromatographic methods,” Carbohydrate Polymers, 2018. View at Publisher · View at Google Scholar