Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 1

Research Article

A Phenylbutenoid Dimer, cis-3-(3′,4′-Dimethoxyphenyl)-4-[(E)-3′′′,4′′′-Dimethoxystyryl] Cyclohex-1-ene, Exhibits Apoptogenic Properties in T-Acute Lymphoblastic Leukemia Cells via Induction of p53-Independent Mitochondrial Signalling Pathway

Table 1

Effect of ZC-B11 on different cell types and the effect of 5-fluorouracil on CEMss cell line expressed as IC50 values in MTT assay after 72 hours. ZC-B11 potently inhibits the growth of T-acute lymphoblastic leukemic cells.

Cell lineTissue of human originCompound IC50 ( g/mL)
ZC-B115-Fluorouracil

CEMssT-Acute lymphoblastic leukemia
MCF-7Human breast adenocarcinoma
MDA-MB-231Human breast carcinoma
HepG2Hepatocellular carcinoma
HeLaCervical carcinoma>50
Human blood mononuclear cells>50