Randomized Controlled Trial of Mindfulness Meditation and Exercise for the Prevention of Acute Respiratory Infection: Possible Mechanisms of Action
Table 1
Stage 1 mediational analysis models for ARI illness global severity and duration: main findings ().
Health indicator
Graphic symbol
Variables
Estimated coefficient
S.E.
value
Sobel test single mediation coefficient (95% CI)
Stage 1 models for ARI illness severity (AUC): potential mediators
Optimism (LOT) score
12
(A) LOT-D1*1
120.8
50.5
0.017*
13
LOT-D2
−110.6
58.8
0.060
11
Group1
−232.4
377.3
0.538
12
Group2*
−471.7
192.4
0.014*
Age
12.8
55.4
0.818
Sex
11.1
347.6
0.975
(B) LOT-D11 ON:
21
Group1*
1.6
0.5
0.001*
()
22
Group2
0.5
0.4
0.246
N/A
Mindfulness (MAAS) score
12
(A) MAAS-D1
−269.4
230.0
0.241
13
MAAS-D2*1
−368.4
151.9
0.015*
11
Group1
365.7
300.2
0.223
12
Group2
−266.4
162.9
0.102
Age
12.1
16.8
0.473
Sex
47.3
203.9
0.817
(B) MAAS-D21 ON:
21
Group1*
0.3
0.1
0.024*
()
22
Group2*
0.3
0.1
0.009*
()
Stage 1 models for ARI illness duration (no. days): potential mediators
Perceived stress (PSS) score
12
(A) PSS-D1
0.01
0.02
0.778
13
PSS-D2*
0.06
0.03
0.023*
11
Group1
0.1
0.2
0.524
12
Group2
−0.3
0.2
0.141
Age*
0.03
0.01
0.033*
Sex
0.06
0.2
0.793
(B) PSS-D2 ON:
21
Group1
−1.6
0.9
0.081
N/A
22
Group2
−1.7
1.0
0.093
N/A
Mental health (SF12M) score
12
(A) SF12M-D1
−0.01
0.006
0.085
13
SF12M-D2*
−0.01
0.002
<0.001*
11
Group1
0.03
0.2
0.864
12
Group2
−0.4
0.2
0.072
Age
0.02
0.01
0.134
Sex
0.006
0.2
0.972
(B) SF12M-D2 ON:
21
Group1
−1.3
6.5
0.842
N/A
22
Group2
4.4
5.5
0.425
N/A
Mindfulness (MAAS) score
12
(A) MAAS-D1
0.02
0.2
0.945
13
MAAS-D2*1
−0.4
0.2
0.037*
11
Group1
0.1
0.2
0.553
12
Group2
−0.3
0.3
0.172
Age
0.03
0.01
0.052
Sex
0.2
0.2
0.374
(B) MAAS-D21 ON:
21
Group1*
0.3
0.1
0.024*
()
22
Group2*
0.1
0.1
0.009*
()
Variables included: health indicator score change at D1 (9 weeks), and D2 (3 months), group status, age, and gender. Results presented only for the models that suggested presence of potential mediation. Sobel testing of indirect effects was conducted only for the identified potential mediators.
1Potential mediator ( for both and pathways). .
