Zuo Jin Wan, a Traditional Chinese Herbal Formula, Reverses P-gp-Mediated MDR In Vitro and In Vivo
Figure 4
Effect of ZJW on intracellular L-OHP accumulation. A validated ICP-MS method was used to detect intracellular L-OHP accumulation in HCT116 and MDR HCT116/L-OHP cells which were treated with ZJW at 25 μg/mL, 50 μg/mL, and 100 μg/mL for 48 h, meanwhile HCT116 cells were taken as control group. The data are representative of at least three experiments, which are presented as the mean ± SD. ZJW (25 μg/mL, 50 μg/mL and 100 μg/mL) versus ZJW (0 μg/mL).
