Resveratrol Is Not as Effective as Physical Exercise for Improving Reproductive and Metabolic Functions in Rats with Dihydrotestosterone-Induced Polycystic Ovary Syndrome
Table 2
Lipid profiles and fasting blood glucose and insulin levels measured after 5 weeks of resveratrol treatment or exercise.
(mmol/L)
Control-vehicle
Control-RSV
PCOS-vehicle
PCOS-RSV
PCOS-exercise
()
()
()
()
( = 9-10)
Cholesterol
2.44 ± 0.10
1.63 ± 0.26**
2.03 ± 0.09
2.05 ± 0.06
2.12 ± 0.14
Triglycerides
0.70 ± 0.11
0.51 ± 0.14
1.53 ± 0.20**
1.35 ± 0.23
1.22 ± 0.13
HDL
1.53 ± 0.10
0.88 ± 0.19*
1.48 ± 0.11
1.38 ± 0.10
1.51 ± 0.12
LDL
0.18 ± 0.03
0.15 ± 0.03
0.23 ± 0.03
0.32 ± 0.03
0.36 ± 0.05
Blood glucose
4.94 ± 0.15
5.33 ± 0.21
5.30 ± 0.08
4.93 ± 0.13
5.14 ± 0.20
Insulin (mU/L)
20.02 ± 2.99
17.81 ± 3.03
19.88 ± 1.68
18.65 ± 0.95
15.74 ± 2.05
HOMA-index
3.85 ± 0.31
3.52 ± 0.39
4.69 ± 0.42
4.19 ± 0.31
3.58 ± 0.47
Values are presented as mean ± SEM. Statistics were calculated using the Mann-Whitney test. *, ** versus control-vehicle. HDL: high-density lipoprotein; LDL: low-density lipoprotein; HOMA: homeostasis model assessment; RSV: resveratrol.
